Search results for "Phosphonium salts"

showing 2 items of 2 documents

Synthèse de pinces à fluorures dérivées d'aminoacides pour l'imagerie TEP

2014

This thesis project, which is part of a collaboration between the Institut de Chimie Moléculaire de l’Université de Bourgogne and the Positron Emission Tomography Research Centre, is about the synthesis of fluoride pincers derived from amino acids based on 18F-B bond construction to get a new class of PET imaging agents. First, this project concerned the design, synthesis and characterisation of new boronato and trifluoroborato phosphonium amino acid salts. Quaternisation of o-boronate phenyl phosphine with β-iodo amino esters or γ-iodo amino ester leads to the corresponding salts without racemisation and in yields up to 88%. Saponification of boronato phosphonium amino esters afford the fr…

Fluoride pincersPhosphonium salts[CHIM.ORGA]Chemical Sciences/Organic chemistry[18F]-radiosynthesisPinces à fluorures[CHIM.ORGA] Chemical Sciences/Organic chemistry[ CHIM.ORGA ] Chemical Sciences/Organic chemistry[CHIM.RADIO] Chemical Sciences/RadiochemistryPhosphonium[18F]-Radiofluoration[CHIM.RADIO]Chemical Sciences/RadiochemistryAminoacidsAminoacides[ CHIM.RADIO ] Chemical Sciences/Radiochemistry
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NMR enantiodifferentiation of triphenylphosphonium salts by chiral hexacoordinated phosphate anions

2003

BINPHAT anion—rather than TRISPHAT—is an efficient NMR chiral shift reagent for triphenylphosphonium salts containing stereogenic centers on the aliphatic side-chain. BINPHAT—rather than TRISPHAT—anion is an efficient NMR (1H and 31P) chiral shift reagent for chiral triphenylphosphonium salts.

Phosphonium saltsBINPHATChiral anionsOrganic ChemistryTRISPHATPhosphateBiochemistryStereocenterchemistry.chemical_compoundNMR enantiodifferentiationTRISPHATchemistryReagentddc:540Drug DiscoveryAmino acids and derivativesOrganic chemistryTetrahedron Letters
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